产品货号：
Z12590
中文名称：
Cathepsin C/CTSC抗体
英文名称：
Anti-Cathepsin C/CTSC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cathepsin C/CTSC Antibody |
| 指标别名 | CTSC;CPPI;Dipeptidyl peptidase 1;CATHEPSIN C |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | CTSC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CTSC recombinant protein (Position:V22-L463). |
| 实际分子量 | 60KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family,a subgroup of the cysteine cathepsins.In humans,it is encoded by the CTSC gene.This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system.Alternative splicing results in multiple transcript variants,at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer.A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme.This enzyme requires chloride ions for activity and can degrade glucagon.Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome,an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. |
| Uniprot ID | P53634 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | cathepsin C |
| 蛋白名全称 | Dipeptidyl peptidase 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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